Developing and validating a method for detecting designer drugs

• Research type

  Research Study

• Full title

  Development and validation of a liquid chromatography, tandem mass spectrometry method for the detection of Cathinone derivatives in human urine

• IRAS ID

  159502

• Contact name

  Rebecca Hopkins

• Contact email

  rebecca.hopkins@nbt.nhs.uk

• Sponsor organisation

  North Bristol NHS Trust

• Clinicaltrials.gov Identifier

  3319, North Bristol NHS R&I

• Duration of Study in the UK

  0 years, 5 months, 1 days

• Research summary

  The study is split into two parts.
  1) The project will develop a method for the detection of some designer drugs of abuse in human urine. Drug free urine purchased as negative control material for clinical applications and purchased pure drug standards from LGC. The method will be fully validated to provide accurate semi-qunatitative results.
  2) The project will then look for designer drugs using the developmed method in anonymised patient urine samples, submitted to the laboratory for clinical purposes. This will test the application of the method and provide information about the prevalance of cathinone use amongst our patient group.

• REC name

  South Central - Hampshire A Research Ethics Committee

• REC reference

  14/SC/1341

• Date of REC Opinion

  24 Oct 2014

• REC opinion

  Favourable Opinion