Developing allogeneic musculoskeletal therapies.

• Research type

  Research Study

• Full title

  Investigating the potential for musculoskeletal tissues and cells isolated from polydactyly patients in the development of novel therapies for cartilage and bone injury and osteoarthritis.

• IRAS ID

  225835

• Contact name

  Karina Wright

• Contact email

  Karina.Wright@rjah.nhs.uk

• Sponsor organisation

  Keele University

• Clinicaltrials.gov Identifier

  21156, AR UK Grant reference number

• Duration of Study in the UK

  19 years, 11 months, 31 days

• Research summary

  Cartilage and bone injury and osteoarthritis continues to take its toll on the quality of life of a large proportion of the world’s population. Clinicians and scientists at the RJAH are part of the Arthritis Research UK Tissue Engineering Centre. We have a long history of developing innovative cell-based therapies for the treatment of cartilage and bone defects and osteoarthritis. To further our studies we wish to collect amputated digits that are removed in the routine treatment of polydactyly at the RJAH. We intend to study the potential of cells derived from these tissues in the treatment of other patients with cartilage or bone injuries or osteoarthritis.

• REC name

  North West - Liverpool Central Research Ethics Committee

• REC reference

  17/NW/0550

• Date of REC Opinion

  6 Oct 2017

• REC opinion

  Favourable Opinion