Develop biomarkers of kidney fibrosis, inflammation, glomerular funct.

  • Research type

    Research Study

  • Full title

    Establish novel non-invasive Magnetic Resonance Imaging kidney biomarkers that may assess the degree of inflammation and / or fibrosis. If successful may lead to possibly replacing invasive tests such as biopsy and / or glomerular filtration rate

  • IRAS ID

    217117

  • Contact name

    Chris Clark

  • Contact email

    christopher.clark@ucl.ac.uk

  • Sponsor organisation

    UCL GOSH Institute of Child Health

  • Duration of Study in the UK

    1 years, 1 months, 26 days

  • Research summary

    Can results obtained from imaging using Magnetic Resonance be used as bio-markers to assess the degree of inflammation, fibrosis and replace some or all of the invasive tests of kidney function, especially biopsy and / or the filtration function of the kidney. In the longer term these bio-markers may identify which patients with Chronic Kidney Disease (CKD) will go into end stage renal failure and so require a kidney transplant or dialysis?

  • REC name

    London - Queen Square Research Ethics Committee

  • REC reference

    18/LO/1800

  • Date of REC Opinion

    18 Jan 2019

  • REC opinion

    Further Information Favourable Opinion