DACC in the Prevention of Surgical Site Infection (DRESSINg)
Research type
Research Study
Full title
A randomised controlled trial to assess the clinical and cost effectiveness of Dialkylcarbamoylchloride (DACC) coated post-operative dressings versus standard care in the prevention of Surgical Site Infection in clean or clean-contaminated, vascular surgery.
IRAS ID
215973
Contact name
James Illingworth
Contact email
Sponsor organisation
Hull and East Yorkshire Hospitals NHS Trust, R&D Department
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Surgical site infections occur in around 5% of patients and have a significant impact on patient morbidity and mortality. They have subsequent consequences on healthcare services in terms of prolonged hospital stays, repeated treatments and increased time dedicated by health professionals. Within vascular surgery, surgical site infection has been reported as high as 20%. With a growing number of multi-drug resistant bacteria, it is imperative for research to focus on novel methods of preventing and treating infection.
Dialkylcarbamoylchloride (DACC) coated dressings are a relatively new wound dressings that work by binding bacteria and removing them from the wound bed when the dressing is removed. Early evidence suggests that this reduced the rate of surgical site infection.
We aim to assess the clinical and cost effectiveness of post-operative wound dressing with DACC-coated dressings vs conventional dressings in clean or clean contaminated vascular surgery.REC name
London - Harrow Research Ethics Committee
REC reference
16/LO/2135
Date of REC Opinion
25 Nov 2016
REC opinion
Favourable Opinion