CVLA Study - Capillary and Venous Lactate Agreement
Research type
Research Study
Full title
CVLA study: Capillary and Venous Lactate agreement - a pilot observational study
IRAS ID
160159
Contact name
Deepankar Datta
Contact email
Research summary
Blood lactate measurement is currently used as a marker of the severity of illness in patients presenting to the Emergency Department. Arterial lactate sampling has been used as the gold standard of measurement for this test. Unfortunately it is uncomfortable for the patient and is not without risk. Peripheral venous lactate measurement is increasingly measured as a substitute for arterial sampling, despite limited research supporting the two samples’ interchangeability. It is easier, but still invasive especially if requiring serial samples or if the patient has difficult venous access. Capillary lactate sampling is a potential solution to the problems of arterial and venous sampling, however it has not been tested in the Emergency Department or clinical setting. Capillary lactate sampling has the potential to improve early patient assessment due to the acceptability of the test to the patient, the ability to get a rapid result, and the low burden on clinical staff in performing the test.
We wish to undertake a pilot study to determine the feasibility of investigating the agreement between capillary and peripheral venous lactate in the Emergency Department.
REC name
South East Scotland REC 02
REC reference
14/SS/1028
Date of REC Opinion
7 Aug 2014
REC opinion
Further Information Favourable Opinion