CURtain

• Research type

  Research Study

• Full title

  Clinical utility of ctDNA in detecting resistance mechanisms and delivering precision medicine: a tumour agnostic study

• IRAS ID

  341778

• Contact name

  Sanjay Popat

• Contact email

  sanjay.popat@rmh.nhs.uk

• Sponsor organisation

  The Royal Marsden NHS Foundation Trust

• Duration of Study in the UK

  2 years, 1 months, 31 days

• Research summary

  The purpose of this study is to establish the clinical utility of implementing circulating tumour DNA (ctDNA) ctDNA testing to identify new resistance mechanisms in patients with metastatic non-small cell lung cancer (NSCLC), sarcoma, gynaecologic and gastrointestinal cancers, and guide choice of subsequent line of therapy in the hope of enhancing delivery of precision-based medicine within the National Health Service (NHS).

• REC name

  London - Dulwich Research Ethics Committee

• REC reference

  24/PR/1320

• Date of REC Opinion

  2 Dec 2024

• REC opinion

  Further Information Favourable Opinion