CUC Research Tissue Bank

• Research type

  Research Tissue Bank

• IRAS ID

  255658

• Research summary

  Research tissue bank in GlaxoSmithKline (GSK)for genotyping and low-interventional sample collection from members of the volunteer panel at the Clinical Unit Cambridge (CUC).

• REC name

  East of England - Cambridge East Research Ethics Committee

• REC reference

  21/EE/0179

• Date of REC Opinion

  3 Sep 2021

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  All samples will be collected using ‘low-interventional’ procedures (resulting in minimal physical burden on the participant during sampling). These may include blood (and cells and/or plasma/serum derived from blood), urine, faeces, breath, tears, saliva, induced sputum. These samples may be used immediately for research projects or stored for future use (including further research unrelated to the original project for which the sample was collected). For each type of sample, we collect, participants will read and sign an Informed Consent From that will include a description of any associated risks. Data will be collected using a health questionnaire and stored securely in GSK databases. For subjects who consent, a blood sample will be taken for genetic analysis; the genetic results will similarly be stored in GSK databases. Only clinical and recruitment staff at the GSK CUC will have access to any personal information associated with these data; only key-coded data (including genetic data) will be available to researchers.

• Research programme

  The bank will be used for GSK-supported research only. Results from tissue bank research projects will be used to support GSK drug development programs. The types of data we will obtain range from evaluation and validation of therapeutic targets to development and validation of methodology to be applied in clinical trials. Our aspiration is to use data to accelerate clinical drug development (and thus get our medicines approved for use in patients more quickly), and to relieve the burden on participants in clinical trials by generating early data relating to our targets and compounds (including information relating to genotypes of patients who may be more or less likely to benefit from our therapies in development).

• Storage license

  12202

• RTBTitle

  Research tissue bank in GlaxoSmithKline (GSK)for genotyping and low-interventional sample collection from members of the volunteer panel at the Clinical Unit Cambridge (CUC).

• Establishment organisation

  GSK Clinical Unit Cambridge

• Establishment organisation address

  ACCI, Box 128, Addenbrooke’s Hospital

  Hills Road

  Cambridge

  CB2 0QQ