Cryopreservation of functional human ovarian tissue

  • Research type

    Research Study

  • Full title

    Development of methodology for cryopreservation of functional human ovarian tissue

  • IRAS ID

    165800

  • Contact name

    Yacoub Khalaf

  • Contact email

    yacoub.khalaf@gstt.nhs.uk

  • Duration of Study in the UK

    1 years, 0 months, 0 days

  • Research summary

    Fertility preservation (FP) is taking an increasingly important role in cancer therapy. Newer therapies have greatly improved cure rate and long-term survival. For many cancer female patients who have not yet started a family, fertility issues are of great concern. Cryopreservation of oocytes or embryos could be currently offered to women of reproductive age who are about to undertake effective cancer treatment that could potentially make them infertile. However, this option requires controlled ovarian stimulation that takes, on average, at least two to three weeks. This can delay the cancer treatment, be physically and emotionally challenging and involve internal scans and examinations that may not be acceptable to young patients. The alternative option could be preservation of ovarian tissues. The development of reliable methods of ovarian tissue preservation will allow patients who cannot afford to delay their cancer treatment to have an option of fertility preservation within 24-48 hours.

  • REC name

    West Midlands - Solihull Research Ethics Committee

  • REC reference

    14/WM/1261

  • Date of REC Opinion

    11 Dec 2014

  • REC opinion

    Favourable Opinion