CREED AF

• Research type

  Research Study

• Full title

  Impact of Cardiac prehabilitation, REhabilitation and patient EDucation on outcomes in patients undergoing first-time AF ablation

• IRAS ID

  318220

• Contact name

  Faizel Osman

• Contact email

  faizel.osman@uhcw.nhs.uk

• Sponsor organisation

  University Hospitals Coventry and Warwickshire NHS Trust

• Duration of Study in the UK

  2 years, 3 months, 30 days

• Research summary

  Atrial fibrillation (AF) is a term used to describe an irregular, and often very rapid, heartbeat. AF increases the risk of a number of diseases associated with the heart and cardiovascular system. Ablation is a procedure to treat AF. It uses small burns or freezes to cause some scarring on the inside of the heart to help break up the electrical signals that cause irregular heartbeats. This can help the heart maintain a normal rhythm.
  Currently patients who are referred for AF ablation do not receive any additional support as part of standard care to improve the outcomes of their ablation procedure. Whereas cardiac rehabilitation is a recognised part of comprehensive care for coronary heart disease patients (patients whose hearts struggle to receive blood), with exercise and education consistently identified as central elements to their rehabilitation. This treatment is not yet recommended for AF ablation patients.
  Therefore, the CREED AF Study is investigating whether a tailored comprehensive exercise and education intervention can improve outcomes in patients who are undergoing first time AF ablation. Central to the CREED AF study is the ‘prehabilitation’ intervention, whereby exercise and education training will be conducted before AND after AF ablation. We are aiming to recruit 106 participants into CREED AF who will be randomised to either receive the CREED AF intervention (exercise and education intervention before AND after AF ablation) or a standard care (control) group. The standard care group will receive a one off 1-to-1 patient education session with a trained practitioner before their AF ablation procedure. This research study does not affect the AF ablation procedure that patients will have as part of their standard of care.

• REC name

  West Midlands - Solihull Research Ethics Committee

• REC reference

  23/WM/0125

• Date of REC Opinion

  1 Aug 2023

• REC opinion

  Further Information Favourable Opinion