CPAP use and exercise capacity in tracheo/bronchomalacia patients
Research type
Research Study
Full title
Does continuous positive airway pressure (CPAP) improve the exercise capacity of adults with tracheomalacia and/or bronchomalacia (TBM)?
IRAS ID
220911
Contact name
Robert Niven
Contact email
Sponsor organisation
University Hospital South Manchester NHS Foundation Trust
Duration of Study in the UK
0 years, 5 months, 1 days
Research summary
People with tracheobronchomalacia have weak airways, which can partially collapse making it difficult for them to get air in or out of their lungs. This can make the person feel extremely breathless and limit their ability to do everyday activities. One way to treat the condition is to apply pressure to the airways using a mask which can help to keep the airways open. \n\nIn this study we want to investigate whether this pressure can help people with this condition to exercise. The participant will complete a walking test 3 times: with CPAP at a low (sham) pressure, a commonly presscribed pressure and a high pressure. We will monitor how far they can walk, how breathless they feel, and their oxygen saturation and heart rate.\n\nThis study will provide information on how this treatment affects exercise capacity, information which could be used to improve treatment for people with this disease in the future.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
17/NW/0452
Date of REC Opinion
1 Aug 2017
REC opinion
Further Information Favourable Opinion