COVID-HEART study [COVID-19] [UPH]
Research type
Research Study
Full title
Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: the COVID-HEART study
IRAS ID
285147
Contact name
John Greenwood
Contact email
Sponsor organisation
University of Leeds
ISRCTN Number
ISRCTN58667920
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Up to 1 in 5 patients hospitalised by COVID-19 have evidence of heart muscle injury as measured from a blood test. This is associated with a high death rate. Using a magnetic resonance imaging(MRI) scan (a type of scan that uses strong magnetic fields and radio waves to produce detailed images of the inside of the heart) we will look at how often, and in what way, the heart becomes damaged, and how the heart recovered 6 months later. We need to know how heart muscle damage and recovery is affected by age, sex, ethnic group and other medical conditions (such as diabetes, high blood pressure, heart disease and narrowing of blood vessels), as these are also known to be associated with high death rates. We also want to see if we can improve the diagnosis of viral heart damage from a simple electrocardiogram (ECG) (a test that is used to check the heart’s rhythm and electrical activity). This could save patients having invasive heart tests which can be uncomfortable, are expensive and carry a small risk of serious complications and may put healthcare staff at increased risk of exposure to COVID-19.\nWe have established a large group of leading UK academic centres which have committed to work together. Recruitment will be linked to the Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes (P-HOSP:COVID-19 Study) which aims to recruit 10,000 patients, 5000 of whom we aim to recruit to these additional research procedures including imaging.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
20/NW/0292
Date of REC Opinion
30 Jun 2020
REC opinion
Further Information Favourable Opinion