COPING study [COVID-19]
Research type
Research Study
Full title
Covid-19 Psychiatry and Neurological Genetics study in the NIHR BioResource, GLAD, EDGI and other recontactable cohorts
IRAS ID
282754
Contact name
Gerome Breen
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
15 years, 0 months, 0 days
Research summary
We propose undertaking crucial mental and neurological health research in relation to the current COVID-19 outbreak in the NIHR BioResource and other recontactable cohorts. In order to explore this in a comprehensive manner, we have designed a set of questionnaires to be administered on a fortnightly basis to consented participants. This will provide us with rich data on the >50,000 participants we anticipate will take part. The baseline questionnaire will take ~30 minutes to complete. We will then ask participants to agree to be recontacted with short questionnaires (5-10 minutes) every fortnight for 24 weeks and following government announcements. This will allow us to track the impact of social isolation, COVID-19 infection and the medium term impact of the economic problems that result. Follow-up questionnaires will include repeated measures of relevant symptoms, behaviours, and mental and physical health outcomes that researchers believe may be exacerbated or affected by the pandemic.\n\nThe studies to be recontacted include participants in the Genetic Links to Anxiety and Depression(GLAD) Study (depression and anxiety disorder cases) and the Eating Disorders Genetics Initiative (EDGI; cases with anorexia nervosa, bulimia nervosa and binge eating disorder as well as other eating disorder diagnoses). Both GLAD and EDGI are studies run by the NIHR BioResource Centre Maudsley, a branch of the NIHR BioResource. Finally, the NIHR BioResource ’general’ cohort consists primarily of patients with inflammatory bowel disorders, as well as healthy individuals recruited ad hoc or from blood transfusion services, many of whom will not have a mental health disorder. Altogether, this will enable us to compare the impact of the pandemic on people with and without mental and physical health conditions.\n\nTo ensure that baseline data is equivalent across cohorts, participants recruited through the NIHR BioResource will additionally be asked questionnaires that were included in GLAD and EDGI sign-up questionnaires.
REC name
South West - Central Bristol Research Ethics Committee
REC reference
20/SW/0078
Date of REC Opinion
27 Apr 2020
REC opinion
Further Information Favourable Opinion