COPEGa Study
Research type
Research Study
Full title
CO2 versus air insufflation in children undergoing Percutaneous Endoscopic Gastrostomy (PEG).
IRAS ID
326461
Contact name
Mike Thomson
Contact email
Duration of Study in the UK
0 years, 11 months, 29 days
Research summary
Percutaneous endoscopic gastrostomy (PEG) has been widely accepted for enteral access since the introduction of the procedure in 1980. The PEG procedure is rapid but requires maximal insufflation of the stomach with air or CO2 (carbon dioxide) in order to tightly attach the gastric wall to the abdominal wall. Percutaneous puncture into the stomach with a needle is conducted under the full insufflated stomach and a gastrostomy tube is placed thereafter. Abdominal distention and pneumoperitoneum are frequent signs after PEG insertion.
Carbon dioxide (CO2) insufflation was initially introduced for colonoscopy and polypectomy in the adult population. CO2 insufflation for endoscopic procedures have also been used for routine colonoscopy, small bowel endoscopy and other endoscopic procedures in paediatric population. Some studies showed that CO2 insufflation reduces the post-procedural abdominal distention and pain without CO2 retention. However there has been no report on the safety and efficacy of CO2 insufflation in PEG procedure in paediatric population.REC name
South West - Central Bristol Research Ethics Committee
REC reference
23/SW/0092
Date of REC Opinion
8 Sep 2023
REC opinion
Further Information Favourable Opinion