Conversion and Neuroinflammation Disorder Observational study (CANDO)
Research type
Research Study
Full title
The influence of inflammation activity and the role of the cerebellum in functional neurological syndromes (Conversion Disorder) - a feasibility study
IRAS ID
261252
Contact name
Christina Van der Feltz-Cornelis
Contact email
Sponsor organisation
University of York
Duration of Study in the UK
0 years, 8 months, 24 days
Research summary
Conversion disorder (CD) or functional neurological disorder is a condition that can present itself in a variety of ways, for example medically unexplained movement problems. It affects in the region of 764,000 people in the UK per year and leads to long-term distress, disability and utilization of health care services. The origin of the disorder is unknown and current treatment options are limited.
We will explore the feasibility of recruiting a cohort of patients who are able and willing to complete questionnaires, give a blood and a hair sample and undergo psycho-diagnostic assessment, and of assessing the role of stress-related systemic low-grade inflammation in the development of motor symptoms associated with the disorder.
All aspects of the feasibility and acceptability to patients of the study and its processes will be examined and the study results will inform the development of a future full trial of anti-inflammatory drugs (AID) as treatment option.REC name
North West - Preston Research Ethics Committee
REC reference
19/NW/0274
Date of REC Opinion
10 Jun 2019
REC opinion
Further Information Favourable Opinion