Conventional vs iassist instrumentation in Total Knee Arthroplasty
Research type
Research Study
Full title
Conventional vs iassist instrumentation in Total Knee Arthroplasty - A randomised controlled trial.
IRAS ID
153227
Contact name
Nikhil Pradhan
Contact email
Sponsor organisation
Warrington & Halton Hospitals NHS trust
Research summary
Total Knee Replacement is a routine surgery performed to relieve pain and improve function in osteoarthritis. One of the key factors determining the long term success of total knee replacement is the alignment of the knee components.
Some studies show incorrect alignment in up to 30% knees. There have been numerous studies describing various techniques to facilitate accurate implantation, but no one technique has been found to be superior. Recently, ‘Internal position sensing technology‘ has been employed in total knee replacement surgery to enable the surgeons to achieve accurate alignment during the procedure. Zimmer ‘iassist’ is one of the knee replacement instrumentation which incorporates this technology and potentially reduce errors in alignment of the component.
The aim of our study is to investigate the accuracy of implant position using ‘iassist’ instrumentation when compared to the currently used conventional standard instrumentation.
Patients requiring total knee replacement will be contacted by a member of the research team. Following informed consent, the patients will be recruited to the study as a participant. The participant will be randomly allocated to one of the two groups, ‘conventional’ or ‘iassist’ group. The patients will undergo standard preoperative investigations which will also include a standing long leg x-ray. The knee replacement prosthesis will be the same for both groups. The postoperative regime will be the same. The participant will be followed up in the clinic at 6 weeks and a postoperative standing long leg x-ray will be obtained.
We would also obtain pain scores using the visual analogue scale at day 1, day of discharge and at 6 weeks. Blood loss and length of stay in the hospital will be estimated and compared between the two groups.
The results will be analysed using the appropriate statistical analysis and results will be presented and published in meetings and peer-reviewed journals.REC name
North West - Preston Research Ethics Committee
REC reference
14/NW/0259
Date of REC Opinion
13 May 2014
REC opinion
Further Information Favourable Opinion