Continuum LINT

  • Research type

    Research Study

  • Full title

    A single centre study comparing continuous interstitial fluid lactate detection (as measured by change in current) to standard measurements of change in venous and arterial lactate in patients undergoing elective coronary artery bypass graft surgery and/or valve replacement.

  • IRAS ID

    346076

  • Contact name

    Anthony Mathur

  • Contact email

    anthony.mathur1@nhs.net

  • Sponsor organisation

    Queen Mary University of London

  • Clinicaltrials.gov Identifier

    NCT06602336

  • Duration of Study in the UK

    1 years, 3 months, 1 days

  • Research summary

    The main goal of this study is to see if a wearable device can reliably track changes in lactate levels in the body. We'll compare the device's readings to standard blood tests to ensure accuracy. If successful, this device could reduce the need for frequent blood tests during surgery recovery, making patients more comfortable. It might also be useful in emergency rooms for quick diagnoses, especially for patients with chest pain.
    This study will take place at Barts Hospital with patients having planned coronary artery bypass graft (CABG) and/ or replacement valve surgery. Participants will wear the sensors on their upper arm, during which the sensors will continuously measure lactate levels. Participants will also have hourly blood samples taken.

    In the future, the data from this new device will be used to train computer algorithms to provide quick responses that help manage a patient's condition, improving future medical care and technology.

  • REC name

    East of England - Cambridge East Research Ethics Committee

  • REC reference

    24/EE/0258

  • Date of REC Opinion

    12 Dec 2024

  • REC opinion

    Further Information Favourable Opinion