Continuous Glucose Monitoring in Pregnancy
Research type
Research Study
Full title
Continuous Glucose Monitoring (CGM) in Pregnancy - a multicentre study\n
IRAS ID
266523
Contact name
Christy Burden
Contact email
Sponsor organisation
North Bristol NHS Trust
Duration of Study in the UK
1 years, 2 months, 1 days
Research summary
Diabetes (high levels of sugar in the blood) can develop in pregnancy in women who have not had it before. It is import to know about because, if it is not treated, high blood sugar levels can cause many complications in the pregnancy; such as: the baby to grow too big, problems during the labour, a higher risk of having a caesarean section, a higher risk of the baby dying during pregnancy(stillbirth) or shortly after birth(neonatal death). It can also cause problems after the baby is born: the baby can have low blood sugars and long-term health problems in later life. \n\nThe number of women with diabetes in pregnancy is increasing as a result of higher rates of obesity and more pregnancies in older women. The stillbirth rate in women with diabetes in pregnancy is more than double, and neonatal death rate nearly 4 times, the general population rate. \n\nAt present, diabetes in pregnancy is diagnosed by a blood test called a glucose tolerance test(GTT) done at 24-28 weeks of pregnancy. Even if this test does not show diabetes some women may go on to develop diabetes later in pregnancy and this has been shown in pregnancies with poor outcomes. Currently, it is not known which is the best test to use for detecting diabetes after 32 weeks of pregnancy. \n\nContinuous glucose monitoring(CGM) provides measures of interstitial glucose. CGM devices provide real time estimates of glucose levels continuously throughout the day and night and have the advantage over intermittent or blood test monitoring of more detailed information on glucose control.\n\nThis study aims to look at the normal levels of glucose in pregnant women with CGM after 32 weeks of pregnancy compared to 20 and 28 weeks of pregnancy, to ultimately investigate the best way to diagnose diabetes at this stage. \n\n
REC name
South West - Frenchay Research Ethics Committee
REC reference
19/SW/0199
Date of REC Opinion
29 Jan 2020
REC opinion
Further Information Favourable Opinion