Contingency management for opioid use disorder
Research type
Research Study
Full title
Mobile telephone-delivered Contingency Management (mCM) to reduce heroin use in individuals with opioid use disorder (CM4OUD)
IRAS ID
343349
Contact name
Carol-Ann Getty
Contact email
Sponsor organisation
King's College London
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 11 months, 14 days
Research summary
RESEARCH AIM
This project aims to (1) develop and test a mobile telephone-delivered Contingency Management (mCM) intervention to reduce opioid use in individuals with opioid use disorder; (2) undertake a trial to determine the feasibility of a larger confirmatory trial of clinical effectiveness, and (3) investigate the dynamic interplay of psychological, environmental, contextual factors and the mCM intervention on influencing heroin use in real-time.BACKGROUND
Opioid use disorder is a major public health issue. Deaths globally from opioid overdose continue to rise, exceeding 100,000 annually. Recovery from opioid use disorder is a long-term and complex process, with the average time in treatment for opiate problems around 2 years longer than for other substances. Contingency Management (CM), where positive reinforcement (i.e., rewards or incentives) is delivered upon evidence of positive behaviour change, is among the most efficacious psychosocial interventions for substance use disorder (SUD). Working alongside a digital health company, a smartphone app will be developed to remotely monitor heroin use and provide positive reinforcement for abstinence.DESIGN
The study will consist of three interlinked workstreams to (1) design, develop and test a new mCM intervention, investigating the usability and functioning of the intervention (2) determine the feasibility of conducting a future confirmatory trial, and (3) investigate the dynamic interplay of psychological, environmental, contextual factors and the mCM intervention on influencing heroin use in real-time.
We aim to recruit service users (approximately 40) undergoing opioid agonist treatment in drug treatment services. Over a 12-week period, participants will receive either (a) treatment as usual or (b) mobile telephone-delivered contingency management.The study is funded by The Society for the Study of Addiction (SSA), as part of the CIs Academic Fellowship.
REC name
West Midlands - South Birmingham Research Ethics Committee
REC reference
24/WM/0216
Date of REC Opinion
24 Oct 2024
REC opinion
Favourable Opinion