Contact Lenses Comfort and Wettability Diurnal Variation

  • Research type

    Research Study

  • Full title

    Spherical and Toric Contact Lenses Comfort and Wettability Diurnal Variation

  • IRAS ID

    341662

  • Contact name

    Michel Guillon

  • Contact email

    MGUILLON@otg.co.uk

  • Sponsor organisation

    CooperVision International Limited

  • Duration of Study in the UK

    0 years, 9 months, 1 days

  • Research summary

    Habitual practice when fitting patients with low level of astigmatism with soft contact lenses is to fit them with spherical contact lenses correcting the average level of myopia (short sight) or hyperopia (long sight) ignoring the low level of astigmatism present. Such practice, whereas successful over many years doe not achieve optimal vision sharpness as shown in a recent study, particularly when lighting is low. A possible drawback of toric contact lenses that also correct astigmatism is that the geometry of their contact lens front surface is more irregular reportedly leading to less contact lens comfort due to the tear film having more difficulty to spread.
    Because of the potential visual benefit of correcting astigmatism, before recommending that approach as a first choice it is important to understand how comfort vary between spherical and toric contact lenses , in particular towards the end of the day when contact lens comfort is poorest.
    The rationale for the study is therefore to compare the comfort achieved with spherical contact lenses to that of toric contact lenses over a full wearing day and to measure how the tear film spreads over the contact lens as it is a significant factor controlling comfort.

    Lay summary of study results:

    The study primary objective was to compare the comfort of toric and spherical contact lenses upon insertion and their variation over up to 10 hours of wear. The results showed that:
    MyDay® toric achieved the same comfort diurnal variation over 10 hours of wear as MyDay® sphere.

    Has the registry been updated to include summary results?: Yes
    If yes - please enter the URL to summary results: Waiting for ISRCTN confirmation.
    If no – why not?:
    Did you follow your dissemination plan submitted in the IRAS application form (Q A51)?: Pending
    If yes, describe or provide URLs to disseminated materials:
    If pending, date when dissemination is expected: 01/12/2026
    If no, explain why you didn't follow it:
    Have participants been informed of the results of the study?: Pending
    If yes, describe and/or provide URLs to materials shared and how they were shared:
    If pending, date when feedback is expected: 31/05/2025
    If no, explain why they haven't:
    Have you enabled sharing of study data with others?: No
    If yes, describe or provide URLs to how it has been shared:
    If no, explain why sharing hasn't been enabled: Not Applicable
    Have you enabled sharing of tissue samples and associated data with others?: No
    If yes, describe or provide a URL:
    If no, explain why: Not Applicable

  • REC name

    London - Surrey Borders Research Ethics Committee

  • REC reference

    24/PR/0373

  • Date of REC Opinion

    23 Apr 2024

  • REC opinion

    Further Information Favourable Opinion