Comparing MFVEP from traditional fixation and video fixation

  • Research type

    Research Study

  • Full title

    Comparing the multifocal visual evoked potential (MFVEP) from healthy volunteers produced from a traditional visual stimulation and that with a central video fixation.

  • IRAS ID

    302875

  • Contact name

    Fatima Shawkat

  • Contact email

    fatima.shawkat@uhs.nhs.uk

  • Sponsor organisation

    University Hospital Southampton Foundation Trust

  • Clinicaltrials.gov Identifier

    3TUVM, Open Science Framework

  • Duration of Study in the UK

    0 years, 7 months, 1 days

  • Research summary

    Children under the age of 8 years old do not have an accurate test to detect issues with their visual pathway. This is because diagnostic tests such as visual fields that are available to adults are too complex for children to understand and be co-operative. The more basic version only can detect large changes, risking under-diagnosis. There is a diagnostic test which is called multifocal visual evoked potentials and requires participants to watch a black and white checkerboard pattern on a TV. A response from the patient brain is then recorded using electrodes that are placed on the scalp. The downside to this test is it can take 5 minutes to record, during which the participant needs to maintain steady fixation. Something that does not easily come to children. This project aims to compares signals recorded using this test with two types of fixation targets; traditional red square and a DVD video target (which should be more child friendly). This will be achieved by using healthy NHS staff volunteers with no pre-existing vision issues to undertake the test with the different targets and statistical analysis will be used to detect if there are any difference between the results. This project can then be the foundation for future projects to test the application in children.

  • REC name

    Yorkshire & The Humber - South Yorkshire Research Ethics Committee

  • REC reference

    23/YH/0075

  • Date of REC Opinion

    2 May 2023

  • REC opinion

    Further Information Favourable Opinion