CoMiTED
Research type
Research Study
Full title
Conservative Management in Traumatic Pneumothoraces in the Emergency Department (CoMiTED): A Randomised Controlled Trial
IRAS ID
312833
Contact name
Edward Carlton
Contact email
Sponsor organisation
North Bristol NHS Trust, Research and Innovation
ISRCTN Number
ISRCTN35574247
Duration of Study in the UK
2 years, 11 months, 30 days
Research summary
A collapsed lung (also known as a ‘pneumothorax’) can occur following trauma such as falls, road traffic accidents or knife injuries. We are doing a study to compare different treatment options for a collapsed lung. Currently, doctors treat this condition by inserting a tube (chest drain) through the chest wall, to help the lung re-inflate. Every year, around 25,000 patients in England and Wales have a chest drain inserted. We think that more patients with a collapsed lung could be safely treated without a chest drain, but there is currently no good research evidence one way or the other. The National Institute for Health Research (NIHR) identified this as an area of need and funded our research study to answer the question.
Both treatments for a collapsed lung (treatment with or without a chest drain) have advantages and disadvantages, but we do not know if one is better than the other. This research will help us find out which treatment is better and whether doctors should change their practice and potentially treat fewer patients with a chest drain.
We are looking for about 750 participants (aged 16 years or older) who have been admitted to Accident and Emergency department (A&E), with a collapsed lung due to injury, to take part in our research.
Participants, when they join the study, will be put into one of two groups. One group will have treatment with a chest drain (current usual care) and the other group will be treated without a chest drain to start with. Participants will have an equal chance of receiving either treatment. All participants will be assessed and monitored according to usual care of this hospital.
Participants will complete questionnaires at 30 days, 3 and 6 months and we will review medical notes.
REC name
Wales REC 4
REC reference
22/WA/0118
Date of REC Opinion
23 May 2022
REC opinion
Further Information Favourable Opinion