Cognitive functioning and adherence to treatment in ESRD
Research type
Research Study
Full title
Investigating cognitive functioning as an obstacle to medication and treatment adherence in patients with end-stage renal disease (ESRD)
IRAS ID
217330
Contact name
Daniel Lamport
Contact email
Sponsor organisation
University of Reading
Duration of Study in the UK
1 years, 7 months, 4 days
Research summary
It has been known since the 1830s that cognitive (i.e., memory and learning) impairments accompany kidney failure, known as end-stage renal disease (ESRD). Although impairments of cognition can have a major impact on quality of life, there has been little attempt to assess this in ESRD, or to understand their nature and the practical implications this may have in the every day life of the person with kidney failure. This study focuses on memory; impairments in memory could have a significant detrimental impact on patients, with particular implications for medication and treatment adherence.
In outline, the methods to be used are as follows:
Tests of prospective memory (remembering actions to be performed in the future); involved in everyday tasks such as remembering to take medication at a certain time and attending doctor's appointments.
Administration of questionnaires to assess mood, general cognitive state, IQ and ability to carry out tasks of daily living, such as cooking and shopping.
REC name
London - Queen Square Research Ethics Committee
REC reference
17/LO/0539
Date of REC Opinion
19 Apr 2017
REC opinion
Favourable Opinion