Cognition and NeuroImaging in neuroDegenerative Disorders (CogNID)
Research type
Research Study
Full title
Cognition and NeuroImaging in neuroDegenerative Disorders (CogNID)
IRAS ID
250525
Contact name
Akram A. Hosseini
Contact email
Sponsor organisation
Nottingham University Hospitals NHS Trust
Clinicaltrials.gov Identifier
Pending, Research database: clinicaltrials.gov
Duration of Study in the UK
2 years, 0 months, 30 days
Research summary
Dementia is a common condition which affects middle aged to elderly individuals who suffer from memory loss and thinking difficulties. There is ongoing research describing methods of diagnosing different types of dementia and the underlying disease processes.
Current psychological assessment tools to diagnose different types of dementia have certain limitations. A recently validated psychological assessment tool, Birmingham Cognitive Screen (BCoS), in stroke patients with memory problems, has shown promise in extending its usage for other purposes.
We aim to prove the usefulness of BCoS in dementia by comparing scores from people with different forms of dementia to determine whether the BCoS can be used to differentiate between them. We will also compare individuals’ scores from the BCoS with scores from other established tests. We believe the BCoS will provide a more complete and accurate profile to help make more timely diagnoses and thus relieve patient uncertainty and distress.Additionally, we aim to improve our understanding of changes in the damage and abnormal functioning of brain cells, in people affected by dementia. We will use cutting edge brain scanning technology, magnetic resonance imaging (MRI) to measure what goes wrong in different parts of the brain and the way groups of cells are damaged.
We will link these changes to dementia patients’ symptoms and the underlying damage to the brain cells. Results from this study will help us better understand how dementia symptoms evolve over time and potentially assess the effectiveness of any new treatments for dementia in the future.REC name
East Midlands - Derby Research Ethics Committee
REC reference
18/EM/0292
Date of REC Opinion
14 Nov 2018
REC opinion
Further Information Favourable Opinion