Clinical outcomes after Traumatic Brain Injury
Research type
Research Study
Full title
Imperial Neurotrauma Centre study of clinical outcomes after Traumatic Brain Injury
IRAS ID
230221
Contact name
David J Sharp
Contact email
Sponsor organisation
Imperial College
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
Traumatic brain injury (TBI) is the leading cause of long-term disability in under 40's. How well a patient recovers following injury remains difficult to predict. Most survivors of TBI are young and have near-normal life expectancy. Hence, the burden on health and social care is substantial. Significant disability at one year has been estimated to have an incidence of 154 per 100,000 of the population, and the acute and on-going costs of TBI are likely to be more than £10 billion per year.
This study aims to predict the clinical outcomes of patients more accurately by investigating the many distinct types of disabilities that can be produced by TBI. We will collect clinical data from patients after TBI in order to assess factors influencing outcomes and complement this routinely collected information with specific neuropsychological, health economic, neuroimaging and fluid biomarker (e.g. blood) data to allow a comprehensive assessment of factors that influence clinical outcomes after TBI.
REC name
London - Camberwell St Giles Research Ethics Committee
REC reference
17/LO/2066
Date of REC Opinion
15 Jan 2018
REC opinion
Further Information Favourable Opinion