Clinical Assessment of a Novel Microprobe Continuous Glucose Monitor
Research type
Research Study
Full title
Clinical Assessment of a Novel Microprobe Array Continuous Glucose Monitor for Type 1 Diabetes
IRAS ID
97260
Contact name
DG Johnston
Contact email
Sponsor organisation
Imperial College London and Imperial College Healthcare NHS Trust
Research summary
The research aims to investigate the use of the novel technology of microprobe arrays in continuous glucose monitoring in type 1 diabetes. A small wearable patch (~1 cm2) containing several microprobes (~ 1000 um in length) will be used to penetrate the outermost skin layer and access tissue fluid without stimulating skin nerve fibers or reaching blood vessels. Research has demonstrated the advantages of this minimally invasive technology in comparison with traditional needles or lancets. Their use is associated with no or minimal pain, no bleeding, minimal tissue trauma and reduced infection risk. Imperial College has developed the existing technology to allow its use as multiple microscopic sensors which can be employed to analyze and monitor glucose content of skin tissue fluid. Using multiple microscopic sensors also provides a larger surface area in comparison to the currently used single macroscopic sensor. This provides the potential for improved accuracy and for its use to analyze other clinically relevant contents of skin tissue fluid.
Our research aims to test the safety and performance of the manufactured microprobes in comparison to commercially available continuous glucose sensors.REC name
London - Stanmore Research Ethics Committee
REC reference
13/LO/0849
Date of REC Opinion
9 Jul 2013
REC opinion
Further Information Favourable Opinion