CHOROID-ROP
Research type
Research Study
Full title
Choroidal vasculature in retinopathy of prematurity
IRAS ID
208979
Contact name
CK Patel
Contact email
Sponsor organisation
R&D Lead, Oxford University Hospitals Foundation Trust
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
PROTECTING THE SIGHT OF PREMATURE BABIES
This project aims to recruit ten premature babies diagnosed with Retinopathy of Prematurity and who are already scheduled for medical examination.
Retinopathy of Prematurity (often abbreviated to ROP) is a condition found in babies born very early (less than 32 weeks) or of very low birth weight (less than 1500g). It affects the development of the blood vessels at the back of the eye and in severe cases can threaten the sight of the new-born child.
Diagnosing ROP is often helped by injecting a fluorescent dye into the bloodstream. The fluorescence at the back of the eye can then be photographed by a special camera before the dye is excreted from the body. In adults, it is now routine to use a special dye – indocyanine green, or ICG – which is particularly useful for revealing the structure of the blood vessels in a deeper layer known as the choroid.
The purpose of this study is to test the use of ICG alongside conventional investigation in babies already at risk from ROP. We hope that this will yield new information about the progress of the disease and hence improve future treatment.
REC name
London - Surrey Borders Research Ethics Committee
REC reference
16/LO/1315
Date of REC Opinion
19 Jul 2016
REC opinion
Favourable Opinion