CHHiP trial data linkage project

• Research type

  Research Study

• Full title

  Accessing and using routine datasets for long term follow-up and late effects in prostate radiotherapy clinical trials-Validation project using data from the phase III Conventional or Hypofractionated High Dose Intensity Modulated Radiotherapy for Prostate Cancer (CHHiP) trial.

• IRAS ID

  295215

• Contact name

  Emma Hall

• Contact email

  emma.hall@icr.ac.uk

• Sponsor organisation

  The Institute of Cancer Research

• Duration of Study in the UK

  4 years, 11 months, 30 days

• Research summary

  Routine patient data including information on cancer diagnosis, treatment, inpatient and outpatient appointments is collated through the National Cancer Registration and Analysis Service (NCRAS). Currently long-term clinical trial follow up data is collected using case report forms (CRFs) to collect data from patients directly by hospital sites or clinical trials units. This data collection is a burden on patients and is expensive for hospitals and clinical trials units.
  The aim of this study is to evaluate whether the routine patient data collated by NCRAS can be used instead of CRFs to undertake long term follow up of patients in clinical trials in pelvic radiothreapy.

• REC name

  London - Central Research Ethics Committee

• REC reference

  21/PR/1349

• Date of REC Opinion

  27 Oct 2021

• REC opinion

  Favourable Opinion