CHElsea II Trial

  • Research type

    Research Study

  • Full title

    A Cluster Randomised Trial of Clinically Assisted Hydration in Patients in the Last Days of Life

  • IRAS ID

    313640

  • Contact name

    Andrew Davies

  • Contact email

    andrew.n.davies@surrey.ac.uk

  • Sponsor organisation

    University of Surrey

  • ISRCTN Number

    ISRCTN65858561

  • Duration of Study in the UK

    3 years, 0 months, 1 days

  • Research summary

    Clinically assisted hydration at the end of life is much debated by healthcare professionals (HCP), it is also a debate that has moved into the public domain, which has caused much contention and anxiety for the dying patient, relatives and Health Care Professionals. The reason for the debate, contention and anxiety, is there is a lack of good quality research, which provides the evidence that guides end of life practice. The CHELsea II trial aims to provide robust data to enable new guidance on the use of assisted hydration in this patient group. The CHELsea II trial is a cluster randomised trial (sites randomised rather than participants) comparing the standard mouthcare with Clinically Assisted Hydration (CAH) versus the standard of mouthcare only in patients who are in the last days of life.

    Delirium can be one of the most distressing aspects of end of life and the CHELsea II trial will uniquely address the specific issue of the use of CAH at the end-of-life and to use an evidence based approach to create a pathway for the majority of end of life patients and to asses the reduction of delirium utilising CAH in this group of patients.

  • REC name

    London - Brighton & Sussex Research Ethics Committee

  • REC reference

    22/LO/0475

  • Date of REC Opinion

    9 Aug 2022

  • REC opinion

    Further Information Favourable Opinion