Characterising General Adult Psychiatry Patients
Research type
Research Study
Full title
Characterising General Adult Psychiatry Patients
IRAS ID
337967
Contact name
David Hayward
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
337967, Project protocol IRAS 337967 v1.docx; 337967, DHedit_CR007-T20 Quantitative Protocol Template v1.0 (1).docx
Duration of Study in the UK
0 years, 8 months, 2 days
Research summary
It is supposed that most patients who attend secondary care General Adult Psychiatry (GAP) services would be excluded from clinical trials because they have too many co-morbidities, they are ‘treatment resistant’, and/or their conditions are too severe.
Hence, it would be helpful to properly measure these metrics in GAP patients using validated rating scales, questionnaires, and a review of the case notes, to see how many GAP patients would be excluded from clinical trials. It is anticipated that this will show that the participants in clinical trials are very different from ‘real life’ GAP patients, and that could explain why the exciting results from many clinical trials do not translate into useful new treatments.
Also, this data could act as a benchmark or baseline against which to measure the efficacy of novel treatments and interventions.
This will be a cross sectional study with the NHS psychiatric diagnoses and co-morbidities noted, then diagnosis-specific rating scales used to measure severity. Treatment resistance will be determined by reviewing the case notes as per the Massachusetts General Hospital-Staging (MGH-S) model for pharmacological treatments, and by noting the modality of treatment, number of sessions, work between sessions, goal-setting, and whether the patient remembers their therapy, the rationale behind it, and a therapeutic alliance with their therapist, for psychological therapies.
Participants will therefore be asked to extend their appointments by about 40 minutes. They will be invited to participate by their usual clinician when they attend an outpatient appointment, or are admitted to psychiatric hospital.
REC name
London - London Bridge Research Ethics Committee
REC reference
24/PR/0221
Date of REC Opinion
2 Apr 2024
REC opinion
Further Information Favourable Opinion