CHAMPION-AF

• Research type

  Research Study

• Full title

  WATCHMAN FLX versus NOAC for EMbolic ProtectION in the Management of Patients with Non-Valvular Atrial Fibrillation

• IRAS ID

  287122

• Contact name

  Timothy Betts

• Contact email

  tim.betts@ouh.nhs.uk

• Sponsor organisation

  Boston Scientfic Corporation

• Clinicaltrials.gov Identifier

  NCT04394546

• Clinicaltrials.gov Identifier

  G200106, IDE No

• Duration of Study in the UK

  7 years, 7 months, 0 days

• Research summary

  The Champion AF study is designed to determine if left atrial appendage closure with the WATCHMAN FLX Device is a reasonable alternative to Direct Oral Anticoagulant (NOACs) in patients with non-valvular atrial fibrillation.

  Patients in this study will be randomized to either receive the WATCHMAN FLX Device or a course of NOACs patients will be assessed over a period of up to 5 years.

• REC name

  East of England - Cambridge East Research Ethics Committee

• REC reference

  20/EE/0237

• Date of REC Opinion

  28 Jan 2021

• REC opinion

  Further Information Favourable Opinion