Cervical Health: The structure and function of the internal os
Research type
Research Study
Full title
The structure and function of the internal cervical os and its implications for cervical insufficiency
IRAS ID
170319
Contact name
Nigel Simpson
Contact email
Sponsor organisation
Leeds Teaching Hospitals NHS Trust
Duration of Study in the UK
4 years, 0 months, 1 days
Research summary
Preterm (premature) birth complicates approximately 1 in 10 pregnancies. The consequences of prematurity on the physical and cognitive development of the child can be significant; the severity of the outcome is dependent on how early the baby is born. One cause of preterm birth is weakness of the neck of the womb. The purpose of this research is to understand the structure of the neck of the womb in the hope of gaining a better understanding of why it may weaken and give way during pregnancy.
Individuals who are eligible for the study are those who are about to undergo a hysterectomy. If an individual has consented to donating their uterus for this study it will not be necessary for them to make any further visits related to the research. Individuals approached will be patients at St James’s University Hospital, a part of Leeds Teaching Hospitals Trust. The research will take place in a University of Leeds laboratory that specializes in biomedical and clinical sciences, which is based on St James’s University Hospital campus. The study will contribute to Ph.D research that is due to last four years.
REC name
Yorkshire & The Humber - Leeds West Research Ethics Committee
REC reference
15/YH/0111
Date of REC Opinion
14 May 2015
REC opinion
Further Information Favourable Opinion