CASCADE II -Version1
Research type
Research Study
Full title
Clinical and Social Characteristics and Demographics in Early Chronic Obstructive Pulmonary Disease.
IRAS ID
182598
Contact name
Lucy Rigge
Contact email
Duration of Study in the UK
1 years, 6 months, 31 days
Research summary
A quantitative study in early Chronic Obstructive Pulmonary Disease (COPD) using a cluster analysis, to establish if prospective, individualised, medical intervention alters projected clinical course.
Chronic Obstructive Pulmonary Disease (COPD) is a condition which causes individuals to suffer from symptoms including chronic cough and progressive breathlessness. In the UK, COPD is predominantly caused by cigarette smoking.
COPD is a major cause of disability and death in the UK, with around 835,000 people currently diagnosed with the disease and an estimated further two million people who suffer from symptoms but do not yet have a diagnosis. COPD causes an enormous symptom burden to patients, and accounts for up to half of emergency admissions to hospital services in England. Whilst COPD is treatable, it is not curable, and emphasis on early diagnosis and intervention provided a key part of the strategy for COPD published by NHS England in 2012. With early diagnosis, the opportunity is provided to intervene with the aim of improving symptoms and exercise tolerance, slowing deterioration and prolonging quality of life.
People with COPD, with a past history of smoking, are at an increased risk of other medical problems. This means it can be challenging to provide them with enough time to fully assess and treat all their problems, particularly due to current pressure on the length of GP appointment times.
The aim of this study is to identify those COPD patients who currently have milder disease and to investigate whether a detailed, medical assessment early in their disease course, which has time to assess all aspects of their care will improve their lung health and general wellbeing.
REC name
North East - Tyne & Wear South Research Ethics Committee
REC reference
15/NE/0213
Date of REC Opinion
7 Jul 2015
REC opinion
Further Information Favourable Opinion