Cardiovascular/COVID-19 - NIHR Health Informatics Collaborative

• Research type

  Research Database

• IRAS ID

  326106

• Contact name

  Jamil Mayet

• Contact email

  jamil.mayet@nhs.net

• Research summary

  Cardiovascular/COVID-19 - NIHR Health Informatics Collaborative

• REC name

  East Midlands - Derby Research Ethics Committee

• REC reference

  23/EM/0150

• Date of REC Opinion

  11 Jul 2023

• REC opinion

  Favourable Opinion

• Data collection arrangements

  The NIHR Health Informatics Collaborative Cardiovascular/COVID-19 Theme utilises de-identified routine healthcare data captured during NHS care. The research database will include clinical, laboratory and demographic data from patients admitted to hospital who have had a troponin test, a B-type Natriuretic Peptide (BNP) test, an echocardiogram, or an outpatient cardiology consultation.

  The dataset will include de-identified routinely collected data electronic health record systems covering:
  - Routine demographic data
  - A&E records
  - Clinical observations (blood pressure, heart rate, oxygen saturation levels etc.)
  - Pathology tests (e.g. Troponin, BNP, Creatinine, Cholesterol, HbA1c, etc.)
  - Echocardiograms
  - Drug treatment
  - Coded discharge summaries
  - Outcome data

  Data will be collated and de-identified at each site, then securely transferred to Imperial College Healthcare NHS Trust where they will be curated into research databases and accessed by approved researchers using the Imperial’s iCARE analytics environment. All data transfers to Imperial College Healthcare NHS Trust will be approved by local data protection offices and Trust Caldecott Guardians under the NIHR HIC data Sharing Framework.

• Research programme

  The NIHR Health Informatics Collaborative Cardiovascular/COVID-19 Theme aims to enable the reuse of data captured during routine NHS care to support research into cardiovascular health. Our NHS research will enable approved researchers to access anonymised data to: 1. Explore ways of improving upon current cardiac diagnostic tools by combining different datasets (A&E, clinical observations, echocardiograms, ward movements, pharmacy administration). 2. Enhance risk stratification of patients presenting with cardiovascular disease, by identifying those in need of urgent intervention and those who could safely be discharged home and investigated further as outpatients. 3. Study the association of several clinical and procedural parameters with in-hospital and longer term outcomes. Our research aims to support care in the future by furthering our understanding of how treatments impact patient outcomes and by enabling clinicians to make more informed data driven decisions when it comes to cardiovascular disease management All researchers accessing the data will do so within the ICHT secure data environment and research projects will be approved by our Scientific Steering Committee.

• Research database title

  Cardiovascular/COVID-19 - NIHR Health Informatics Collaborative

• Establishment organisation

  imperial College Healthcare NHS Trust

• Establishment organisation address

  Joint Research Compliance Office, Imperial College London and Imperial College Healthcare NHS Trust

  Imperial College London and Imperial College Healthcare NHS Trust

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