Cardiovascular risk profiles in Cardiac Rehabilitation patients
Research type
Research Study
Full title
Cardiovascular and respiratory adaptations in response to a standard UK exercise based cardiac rehabilitation.
IRAS ID
126483
Contact name
Lee Ingle
Contact email
Sponsor organisation
University of Hull
Research summary
Cardiovascular disease accounts for 190,000 deaths annually and is the largest cause of death in the UK (Scarborough et al. 2010) and although mortality rates from cardiovascular disease have declined, the UK is still behind many other developed countries (NICE, 2010). Following a cardiac event patients can participate in Cardiac Rehabilitation which takes a multifaceted approach to the restoration of patient health and well-being by modifying cardiovascular risk factors associated with disease progression (American Association of Cardiovascular and Pulmonary Rehabilitation [AACVPR], 2006). Exercise has been accepted as an integral part of Cardiac Rehabilitation and is regarded as a key element of the Cardiac Rehabilitation process (British Association for Cardiovascular Prevention and Rehabilitation [BACPR], 2012).
However, gaps in the understanding of Cardiovascular and cardio-respiratory adaptations to Cardiac Rehabilitation have been highlighted (Sandercock, Hurtado & Cardoso, 2011) and variable study outcomes suggest that there is no coherent understanding of the training conditions required to elicit beneficial physiological and cardio-respiratory changes (Taylor et al. 2004 & Heran et al. 2011). Even though various mechanism have been suggested as moderators for increased cardio-respiratory fitness and there has been no study that systematically analysed factors with the potential to modulate these changes (Sandercock, Hurtado & Cardoso, 2011) and the specific mechanisms resulting in any benefits are largely elusive (AACVPR, 2006). It has been suggested that studies placing subjects at low intensities of exercise would facilitate (Swain & Franklin, 2001) the investigation of physiological and cardio-respiratory mechanism of change. This study will identify the cardiovascular and cardio-respiratory changes that occur as a result of a typical UK Cardiac Rehabilitation exercise programme.We will recruit patients recently discharged from hospital with a cardiac diagnosis or stepped change in condition to identify whether a standard UK Cardiac Rehabilitation improve cardio-respiratory fitness and what mechanism are responsible?
REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
13/YH/0278
Date of REC Opinion
27 Sep 2013
REC opinion
Further Information Favourable Opinion