Cardiovascular Risk and other Comorbidities in Asthma (V 1.0)
Research type
Research Study
Full title
An Evaluation of Cardiovascular (CV) Risk and other Comorbidities in Asthma: A Cross Sectional Study
IRAS ID
324725
Contact name
Nichola Gale
Contact email
Sponsor organisation
Cardiff University
Duration of Study in the UK
1 years, 2 months, 1 days
Research summary
Background
Asthma is a condition affecting the lungs, causing episodes of wheezing, coughing, and breathlessness. Asthma is frequently associated with a number of other conditions such as heart disease, high blood pressure, increased body weight, diabetes, and decreased physical activity. This study aims to assess the risk of heart disease in asthma patients by measuring blood pressure over 24hrs in people with asthma compared to people without asthma. How this links to lung function, weight, and reported physical activity levels and asthma control will be analysed.Methods
Methods
A volunteer sample 30 people with asthma will be recruited through the NHS. Additionally, 30 people without asthma will take part. Participants will undertake one assessment of blood pressure over 24hrs, this involves wearing a cuff on the upper arm which inflates hourly. The following will be assessed once: height, weight, muscle and fat mass, lung function, and airway inflammation will be measured by two breathing tests; the six-minute walk test will be completed, with breaks as needed. All participants will complete a physical activity questionnaire, and people with asthma will complete a respiratory quality of life and asthma control test questionnaire.All procedures will be assessed for risk, and data will be retained securely.
Dissemination
Research results will be submitted to academic journals, presented at conferences, and presented as a PhD thesis.REC name
HSC REC B
REC reference
23/NI/0141
Date of REC Opinion
6 Nov 2023
REC opinion
Further Information Favourable Opinion