Cardio-renal imaging after cardiogenic shock
Research type
Research Study
Full title
A pilot study of cardio-renal imaging following cardiogenic shock complicating acute myocardial infarction.
IRAS ID
262055
Contact name
Colin Berry
Contact email
Sponsor organisation
Beardmore Centre for Health Sciences
Clinicaltrials.gov Identifier
Duration of Study in the UK
3 years, 0 months, 1 days
Research summary
The overall aim of the imaging in this study is to assess how the kidneys and hearts of people admitted with i) uncomplicated heart attacks and ii) serious heart attacks and low blood pressure (cardiogenic shock) recover following treatment. We will analyse the characteristics of myocardial infarction (’heart attack’), heart pump function and remodelling, kidney size, perfusion and function, and correlate these findings with other parameters of health outcomes, including bloods tests such as NT-proBNP, renal function, and New York Heart Association heart failure grade. This pilot study aims to gather information on feasibility of the cardio-renal protocol in patients with uncomplicated heart attacks and in those who have survived cardiogenic shock (heart attack with low blood pressure and adverse signs). \nCurrently sick patients tolerate current MRI protocols poorly. The purpose of this innovative MRI pilot study is to create new possilbilities for cardio-renal imaging in a very high risk sub-group that is not normally considered for this diagnostically useful type of imaging. Accordingly, in that study, we will employ the most recent, state-of-the art methods (e.g. non-breath-hold free breathing where feasible) to reduce scan duration.
REC name
North of Scotland Research Ethics Committee 1
REC reference
19/NS/0160
Date of REC Opinion
2 Oct 2019
REC opinion
Favourable Opinion