Cardiac MRI study of adults late after childhood anthracycline therapy

• Research type

  Research Study

• Full title

  Cardiac MRI for quantifying diffuse myocardial fibrosis in adult patients, late after childhood anthracycline chemotherapy.

• IRAS ID

  131221

• Contact name

  Marina Louise Hughes

• Contact email

  marina.hughes@gosh.nhs.uk

• Sponsor organisation

  Great Ormond Street Hospital for Children NHS Foundation Trust

• Research summary

  Anthracycline medicines are effective cancer treatment, but cause an important side-effect: damage to heart muscle cells. Echocardiography has been used to monitor the general heart function of patients anthracycline treatment, but until now, the only direct method of assessing the muscle cell damage has been a biopsy of the heart muscle.

• REC name

  London - City & East Research Ethics Committee

• REC reference

  13/LO/0961

• Date of REC Opinion

  15 Jul 2013

• REC opinion

  Favourable Opinion