Cardiac MRI During Dialysis
Research type
Research Study
Full title
Dynamic effects of online HDF on cardiac function and myocardial perfusion utilising cardiac MRI
IRAS ID
145705
Contact name
Maarten W Taal
Contact email
Research summary
Haemodialysis (HD),which is blood purification for those with kidney failure, is known to lead to damage to the heart through compromised blood supply which is cumulative over time. Studies have demonstrated this in a variety of ways before and after sessions of dialysis but few have been able to show the effects on the heart during dialysis in any detail. Haemodiafiltration (HDF) is a type of dialysis which is thought to be relatively more protective to the heart, but again there is a lack of evidence of the effects on the heart actually during dialysis.
We have developed the ability to perform detailed heart MRI scanning whilst patients are having dialysis and therefore we intend to conduct a pilot study with 12 patients, scanning them whilst they are receiving both standard HD and HDF to assess their relative effects on the heart.
REC name
East Midlands - Derby Research Ethics Committee
REC reference
14/EM/0166
Date of REC Opinion
9 May 2014
REC opinion
Favourable Opinion