Cardiac MR Phosphorous Spectroscopy in Breast Cancer Patients

  • Research type

    Research Study

  • Full title

    Can MR Phosphorous Spectroscopy tell us if the drugs used to treat breast cancer patients are adversely affecting their heart function?

  • IRAS ID

    156570

  • Contact name

    Gillian MacNaught

  • Contact email

    Gillian.Macnaught@ed.ac.uk

  • Research summary

    Breast cancer patients are treated with a combination of different drugs that unfortunately can harm their heart and in some cases can cause heart failure. To limit the damage from these drugs on the heart, it is important for the doctors to know how well the heart is working before, during and after treatment. Imaging the heart using Magnetic Resonance Imaging (MRI)can tell us how well the heart is pumping blood to the rest of the body. If the heart has been harmed then it is likely that less blood will be pumped out of the heart. We would like to test another MRI technique called Magnetic Resonance Phosphorous spectroscopy (31P-MRS). This has the potential to tell us how well the cells of the heart are working and could give us an earlier warning that the patient’s heart is at risk of damage. Their cancer treatment could then be changed before further damage is done to their heart.

  • REC name

    South East Scotland REC 02

  • REC reference

    14/SS/1041

  • Date of REC Opinion

    1 Sep 2014

  • REC opinion

    Further Information Favourable Opinion