CanRisk-GP

  • Research type

    Research Study

  • Full title

    CanRisk-GP: a feasibility study of incorporating multifactorial breast cancer risk assessment into general practice

  • IRAS ID

    326051

  • Contact name

    Juliet Usher-Smith

  • Contact email

    jau20@medschl.cam.ac.uk

  • Sponsor organisation

    Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

  • Duration of Study in the UK

    1 years, 11 months, 31 days

  • Research summary

    Breast cancer represents a significant burden of disease in the UK. The national breast screening programme starting at age 50 and enhanced referral pathways for those known to be at increased risk, mainly due to family history, help with early detection and treatment. Still, most women developing breast cancer do not have relevant family history and are not aware of their increased risk. The CanRisk tool combines different data about women to help doctors predict their future risk of developing breast cancer. CanRisk is widely used in specialist clinics for women known to be at increased risk. This study focuses on whether and how CanRisk could help stratify breast cancer risk in general practice so more women can benefit from resources available to them from age 40 to help manage and reduce their risk.
    We will invite women between 40 and 50 years old who are not aware that they have known risk factors for breast cancer and are registered at GP practices across Cambridgeshire and Peterborough to join this study.
    Women taking part in this study will complete a CanRisk assessment using a user-friendly version of the CanRisk tool called MyCanRisk. Women at increased risk of developing breast cancer will be advised to attend a GP appointment to discuss what steps they can take to reduce their risk and, if appropriate, they will be referred to specialist care. We will measure women’s interest and availability to learn about their breast cancer risk, ask them about their experience completing MyCanRisk and assess the consequences that undergoing this assessment may have for them. We will also reflect on how GP appointments go and ask GPs, as well as broader practice staff, what they think of CanRisk and how it works in general practice.

  • REC name

    East of England - Cambridge Central Research Ethics Committee

  • REC reference

    23/EE/0199

  • Date of REC Opinion

    25 Oct 2023

  • REC opinion

    Further Information Favourable Opinion