BREATHE study (Biofeedback Reactivity and Awareness To HEalth)

  • Research type

    Research Study

  • Full title

    BREATHE feasibility study (Biofeedback Reactivity and Awareness To HEalth): The effect of biofeedback and mindfulness breathing on blood pressure and psychological wellbeing

  • IRAS ID

    324891

  • Contact name

    Pankaj Gupta

  • Contact email

    pankaj.gupta@uhl-tr.nhs.uk

  • Sponsor organisation

    UHL Sponsor

  • Clinicaltrials.gov Identifier

    https://doi.org/10.17605/OSF.IO/JY32C, OSF

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Hypertension is a global issue affecting 1.28 billion people worldwide (WHO, 2023) and is a preventable risk factor for stroke and death. Uncontrolled blood pressure is a serious health issue that needs to be addressed. Medication alone is not always sufficient to control blood pressure, with other approaches needed. It is crucial that patients are able to control their blood pressure to reduce the risk of health complications and premature death. Research suggests that biofeedback is a potentially viable option for patients with hypertension and anxiety.

    Biofeedback is an intervention where a person receives feedback on their physiological responses e.g., heart rate in relation to activities. For example, a person looks at their heart rate via the Fitbit, practices breathing practice, then looks again at the Fitbit for their heart rate to see how it has changed. The “biofeedback” is the device’s feedback to show how an activity can affect the person’s heart rate. It acts like positive reinforcement, showing how an activity can improve their heart rate.

    We will look at the effect of biofeedback in patients with uncontrolled blood pressure and prescribed multiple anti-hypertensive medications. The intervention group will practice biofeedback with breathing at home for three months using a Fitbit. The control group will have a hypertension educational session and wear the Fitbit for three months but will receive no guidance about biofeedback or breathing. This will compare Fitbit + breathing biofeedback vs Fitbit alone.

    The will be a pilot study, trialling the intervention and study design before expanding it into a larger RCT. We will recruit 40 participants. If the intervention is successful, it will provide an additional therapy option for people who struggle to take medication or do not experience the desired effects of blood pressure (e.g., blood pressure control).

  • REC name

    North of Scotland Research Ethics Committee 2

  • REC reference

    24/NS/0027

  • Date of REC Opinion

    26 Mar 2024

  • REC opinion

    Further Information Favourable Opinion