Brain Physics Database v1
Research type
Research Database
IRAS ID
320219
Contact name
Peter Smielewski
Contact email
Research summary
Brain Physics Database
REC name
Yorkshire & The Humber - Leeds East Research Ethics Committee
REC reference
23/YH/0085
Date of REC Opinion
25 Apr 2023
REC opinion
Favourable Opinion
Data collection arrangements
The content of the database will include de-identified physiological monitoring data, de-identified clinical variables and monitoring device variables of adult and paediatric patients with acute brain injury or cerebrospinal fluid disorders admitted to CUH. Monitoring data are represented by high frequency physiological measurement collected during neuromonitoring activities (e.g arterial blood pressure waveforms, ECG waveforms etc). Monitoring data can be waveforms or numeric data. Clinical descriptors stored in the database will depend on the pathology under investigation (e.g. type of injury, severity of injury metrics etc) . Clinical descriptors will be extracted from the EHR and de-identified by the clinical informatics department on regular basis. Monitoring device variables will include information like device settings, make and model etc.
Research programme
The Database will support the research pursued by the investigators in the Brain Physics Lab group. The data will be used for clinical research on various dynamical properties of cerebral blood flow and cerebrospinal fluid circulation. There are many clinical areas where such research has a tangible impact. Examples are adult and paediatric acute brain injury, such as traumatic brain injury, and cerebrospinal fluid disorders, such as normal pressure hydrocephalus.
Research database title
Brain Physics Database
Establishment organisation
Cambridge University Hospitals NHS Foundation Trust
Establishment organisation address
Cambridge Biomedical Campus
Hills Road
Cambridge
CB2 0QQ