Bone Metastasis Audit (BoMA) Database
Research type
Research Database
IRAS ID
234457
Contact name
Samantha Downie
Contact email
Research summary
Bone Metastasis Audit (BoMA) Database
REC name
West of Scotland REC 4
REC reference
20/WS/0044
Date of REC Opinion
10 Mar 2020
REC opinion
Favourable Opinion
Data collection arrangements
Data is already being collected and analysed in local health boards by research staff (under Caldicott Guardian approval) for the purposes of local care improvement and audit. We seek permission to uploade anonymised, de-identified information from local bone metastasis registries to a central location, held securely within the Lothian Research Safe Haven (LRSH). This will create the central, national Bone Metastasis Audit (BoMA) data registry which will contain only non-identifiable data. No patient identifiable information will ever leave the originating NHS Health Board. Analysis of this anonymised data from multiple centres will allow us to assess, compare and standardise care, initially across the East of Scotland, but extending to other centres in Scotland and the UK over the three-year study period.
Research programme
The British Orthopaedic Oncology Society recommends that each orthopaedic centre in the UK has a named consultant responsible for managing patients with metastasis-related fractures. They also call for a standardisation of techniques for surgical management of bone metastases and recommend that data is collected nationally to assess outcomes and maximise evidence-based management. The BoMA database will be the first data registry within the UK to seek to address this aim. By the end of the first two years of the project (31/12/2021), the BoMA database will contain records for almost 2000 patients (three centres from 2010-2021, 1,925 participants) and will continue to collect data for 175 patients/year on a retrospective basis. Access to the data will support the Chief Investigator S Downie, in her PhD with the University of Edinburgh. In addition, any requests for access to anonymised data within the secure-access platform of the LRSH will be considered by the database custodians on a case-by-case basis. No identifiable data will be released to any researcher. This database will provide an excellent basis for local healthcare improvement, standardisation of care and a method of monitoring the effect of any novel therapies in this common and life-threatening disease.
Research database title
Bone Metastasis Audit (BoMA) Database
Establishment organisation
Lothian Research Safe Haven (LRSH)
Establishment organisation address
The Queen's Medical Research Institute
47 Little France Crescent
Edinburgh
EH16 4TJ