Blood levels of fatty acids after 2 forms of cod liver oil, v1

  • Research type

    Research Study

  • Full title

    Comparison of plasma levels of n-3 fatty acids after ingestion of an emulsified cod liver oil product and a non emulsified cod liver oil product (HMR code: 14-029)

  • IRAS ID

    176746

  • Contact name

    Frans van den Berg

  • Contact email

    fvandenberg@hmrlondon.com

  • Sponsor organisation

    GSK

  • Duration of Study in the UK

    1 years, 0 months, 0 days

  • Research summary

    Omega 3 fatty acids (also known as ‘good fats’) are found in oily fish, and some nuts and seeds. Eating food rich in good fats helps to maintain a healthy diet, and can protect against heart disease. Some food supplements, like cod liver oil, are also high in good fats, and many people take them to top up the amount of good fats in their diet.

    In this study, we’ll compare in 50 healthy men and women, aged 18–45 years, blood levels of fatty acids after a mixed and a non–mixed form of cod liver oil.

    Participants will have 2 study sessions. In one session, they’ll take the mixed form of cod liver oil; in the other, they’ll take the non mixed form. For 3 days before each session and until the end of the session, participants will eat a diet that’s low in good fats, so that we can measure more accurately the amount of fatty acid released from the cod liver oil.

    There’ll be at least 11 days between each study session. Participants will take up to 5 weeks to finish the study. They’ll make 3 outpatient visits, and stay on the ward for 1 night in each study session (2 nights in total). We’ll also phone them about 7 days after their second session.

    A pharmaceutical company (GlaxoSmithKline Research and Development Ltd) is funding the study.

    The study will take place at 1 centre in London

  • REC name

    Wales REC 1

  • REC reference

    15/WA/0127

  • Date of REC Opinion

    7 May 2015

  • REC opinion

    Further Information Favourable Opinion