Bladder Cancer Biomarkers

  • Research type

    Research Study

  • Full title

    New cancer biomarkers for the diagnosis, prognosis and monitoring of drug treatment response in bladder cancer.

  • IRAS ID

    125963

  • Contact name

    Hardev Pandha

  • Contact email

    H.Pandha@surrey.ac.uk

  • Sponsor organisation

    University of Surrey

  • Research summary

    It is not currently possible to eradicate HIV in the majority of patients because even with the best antiretroviral treatment there is still a small reservoir of virus hidden in some cells of the body. One problem is that the methods available to measure this reservoir and also to evaluate how the virus hides in the cell are very poor. This study is being done to develop new methods to examine the sites where the virus hides in the cell, to measure how much virus there is in this reservoir and to help explain how HIV avoids being eradicated by treatment. HIV-1 genetic material will be measured in four different HIV patient groups in blood and gut tissue samples. Gut tissue is the major compartment of the HIV-1 reservoir in infected patients and an important place to assess how any new tests might help scientists find new treatments for HIV in the future.

  • REC name

    London - Brent Research Ethics Committee

  • REC reference

    13/LO/0739

  • Date of REC Opinion

    9 Aug 2013

  • REC opinion

    Further Information Favourable Opinion