Biomarkers and Rapid Imaging in Dementia Diagnosis: B-RAPIDD
Research type
Research Study
Full title
Biomarkers and Rapid Imaging in Dementia Diagnosis: B-RAPIDD
IRAS ID
291170
Contact name
Nick Fox
Contact email
Sponsor organisation
University College London
ISRCTN Number
ISRCTN12777415
Clinicaltrials.gov Identifier
UCL Data Protection Registration , Z6364106/2021/06/218
Duration of Study in the UK
3 years, 0 months, 0 days
Research summary
Dementia diagnosis typically starts in memory clinics with blood tests, cognitive assessment and scanning using MRI or CT scans. Diagnosis, and MRI scanning in particular, is time consuming and expensive, with pressure to reduce the duration and cost of imaging and to increase the general efficiency of the process. MRI is the imaging method of choice, but these pressures massively limit its use, contributing to widespread diagnostic performance variation between hospitals. In addition, a number of people do not tolerate standard MRI scans due to their prolonged duration. B-RAPIIDD enhances the information obtained from new ultra-fast MRI scanning using a new machine learning approach, resulting in a cost-effective, efficient, and widely deployable early diagnostic assessment for all. Potential participants are people undergoing standard investigations for memory and thinking difficulties at the Cognitive Disorders Clinics at the National Hospital for Neurology and Neurosurgery, UCLH. Participants will be asked to have an additional 7 min scan (following their routine scan) and a blood test.
REC name
London - Hampstead Research Ethics Committee
REC reference
21/LO/0815
Date of REC Opinion
11 Jan 2022
REC opinion
Further Information Favourable Opinion