Biology of dying - analysis of stored samples
Research type
Research Study
Full title
Biology of dying - analysis of stored samples
IRAS ID
321780
Contact name
Seamus Coyle
Contact email
Sponsor organisation
The Clatterbridge Cancer Centre NHS Foundation Trust
Duration of Study in the UK
10 years, 0 months, 1 days
Research summary
We have collected urine from patients with advanced cancer towards the end of life from 2 prior studies. Unfortunately, during a recent HTA inspection of the University, they informed us that our prior REC approvals were no longer valid. The law changed during covid. The recruitment to our studies also stopped during covid. At the time it was not possible to analyse the samples. We therefore don’t have current ethics to analyse the samples.
From the work so far, we have identified multiple metabolites that change in the last weeks and days of life. We have submitted a patent on these and are in the process of developing a hospital based test.
This proposal is a request to further analyse existing samples that are stored at the University of Liverpool.REC name
Wales REC 7
REC reference
23/WA/0036
Date of REC Opinion
9 Jan 2023
REC opinion
Favourable Opinion