BioAID 2024-2029

• Research type

  Research Tissue Bank

• IRAS ID

  343977

• Research summary

  BioResource in Adult Infectious Disease (BioAID) 2024-2029

• REC name

  South Central - Oxford C Research Ethics Committee

• REC reference

  24/SC/0207

• Date of REC Opinion

  19 Jul 2024

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  The Bioresource for Adult Infectious Diseases (BioAID) is a collaborative project between multiple NHS Hospitals in partnership with closely affiliated UK Universities. BioAID (2024-2029) aims to collect biological samples and clinical information from episodes in which patients present to hospital with a suspected or confirmed infectious disease. Participants will be asked to give consent to have their samples and clinical information collected within BioAID. The samples will be
  used to analyse gene expression, protein measurements and individual immune responses. In addition, the samples will be used to obtain the participants genetic code and the germ causing the illness where possible. Consent will be obtained either at the time of recruitment, or using "deferred consent". Consent or consultee declaration for inclusion of patients will be requested within 14 days of the collection of research samples. Data and or samples from patients for whom consent/consultee declaration is not provided within 28 days will be deleted/destroyed and excluded from any analysis.

• Research programme

  Infectious diseases in adults remains an important burden for health care in the UK. Further research is needed in order to improve the diagnosis of these diseases, and improve our understanding of the factors which are responsible for severe disease and failure to respond to current treatments. We aim to establish a tissue bank of targeted infectious diseases across major biomedical research centres within the NHS, linking information about each patient’s illness with samples that can be used to investigate the patient’s genetic (DNA) profile, their response to infection and the microbial organism. This will provide an invaluable bioresource to evaluate new strategies for diagnosis of infectious diseases and predicting the outcome of specific diseases in individual patients. We will also establish the framework for research sampling and data collection to complement existing studies in infectious diseases, and inform the design of new studies as well as provision of NHS services for infectious diseases.

• Storage license

  N/A

• RTBTitle

  BioResource in Adult Infectious Disease (BioAID) 2024-2029

• Establishment organisation

  University College London

• Establishment organisation address

  Gower Street

  London

  WC1E 6BT