Bio-Min in white spot lesions
Research type
Research Study
Full title
The effectiveness of Bio-Min toothpaste in the management of white spot lesions: A Randomized Control Trial
IRAS ID
284589
Contact name
Ama Johal
Contact email
Sponsor organisation
Queen Mary University London
ISRCTN Number
ISRCTN14479873
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
2 years, 6 months, days
Research summary
Young people undergo orthodontic treatment to improve the appearance of their teeth, smile and bite. It is therefore very sad to see so many of these teeth become harmed during brace treatment, leaving a permanent and visible mark, which becomes very easy to see after brace removal. Toothpaste is recommended and used daily and therefore remains a relatively easy method of improving the appearance of the teeth by lessening the visibility of these marks. Whilst traditional Fluoride containing toothpastes have been shown to have some beneficial effects, newer bio-active glass toothpastes which contain lower levels of fluoride but a greater potential to release this in a more gradual way, offer the possibility of greater improvements in reducing these defects in the teeth.
We aim to assess how brushing your teeth with one of two different types of toothpaste can affect the appearance of the white spots defects, known as white spot lesions (WSL), that have developed on the teeth and become visible following the removal of your fixed brace.REC name
Wales REC 6
REC reference
21/WA/0256
Date of REC Opinion
6 Sep 2021
REC opinion
Further Information Favourable Opinion