Avon Community Acquired Pneumonia General Practice part 2, AvonCAP GP2
Research type
Research Study
Full title
Establishing the burden of vaccine preventable acute lower respiratory tract infections in primary care, UK
IRAS ID
305956
Contact name
Adam Finn
Contact email
Sponsor organisation
University of Bristol
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 11 months, 2 days
Research summary
Little is known about the burden of vaccine preventable chest infections in primary care. We want to understand how frequently adults present to primary care with chest infections; how people rate their health while they are ill; how many of these illnesses could be prevented by vaccination and what groups of patients might benefit most.
A preparatory study called ‘AvonCAP GP1’ is underway to improve how chest infections are recorded in primary care records, allowing us to accurately estimate the number of patients with these infections and the burden that they have on patients and on the NHS.
We have selected GP practices in Bristol with patients from different backgrounds, ethnicities and living in a range of circumstances (e.g. affluent/deprived). We will include people who: are aged 18 or older; contact their GP practice or out-of-hour provider with a recent onset illness (symptoms for less than 28 days); and have symptoms suggestive of a chest infection, worsening of heart failure or presumed “non-infective” worsening of chronic lung disease (e.g. asthma or COPD). The latter two are included as they may be caused by infection.
The study has two parts: surveillance, where we will collect information about patients and their medical history/symptoms from their GP records; and a sampling study where we will invite patients to give nose, throat, saliva and urine samples and to complete surveys about their illness and quality of life. All eligible patients will be invited to take part in both parts.
The study is running alongside her sister study, ‘Avon CAP’, which is capturing patients admitted to hospital with chest infections in Bristol. These studies are of heightened importance due to the COVID-19 pandemic and will complement each other by providing comprehensive information about patients presenting to both primary and secondary (hospital) care with chest infection.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
21/YH/0271
Date of REC Opinion
1 Dec 2021
REC opinion
Further Information Favourable Opinion